Developing novel therapeutic strategies for ovarian cancer

Therapeutic approaches for ovarian cancer have often focused on the use of cytotoxic compounds that preferentially kill rapidly dividing cells. These treatments also affect various healthy tissues and are often ineffective at completely clearing cancer cells.

We develop new therapeutic strategies that aim to reshape the cellular landscape throughout the tumour microenvironment and counter adaptive mechanisms used by cancer cells to evade immune detection and resist therapies. In close collaboration with chemists and immunologists, we focus on an array of treatment approaches, from novel molecules, to biologics, and engineered cell therapies.

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Tracking cellular adaptation and acquired resistance